A heme-degradation pathway in a blood-sucking insect
نویسندگان
چکیده
منابع مشابه
A heme-degradation pathway in a blood-sucking insect.
Hematophagous insects are vectors of diseases that affect hundreds of millions of people worldwide. A common physiological event in the life of these insects is the hydrolysis of host hemoglobin in the digestive tract, leading to a massive release of heme, a known prooxidant molecule. Diverse organisms, from bacteria to plants, express the enzyme heme oxygenase, which catalyzes the oxidative de...
متن کاملA novel heme degradation pathway in a blood-sucking insect
Instituto de Bioquímica Médica, Programa de Biologia Molecular e Biotecnologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, 21941-590, Brazil Department of Biological Sciences, University of Texas at El Paso, El Paso, TX 79968-0519, USA Departamento de Parasitologia, Universidade de Sao Paulo, Sao Paulo, SP 05508-900, Brazil Departamento de Fisiologia e Farmacodinâmica, Instituto Os...
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Self-mutilation is defined as intentional damaging of the body without intention to die. Patients with borderline personality disorder frequently mutilate themselves by means of cutting, burning and abrading their skin. In this case report, a patient with borderline personality disorder is described who has cut his skin and suck his blood Several times. He had also the history of killing pigeon...
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Heme and iron are essential molecules for many physiological processes and yet have the ability to cause oxidative damage such as lipid peroxidation, protein degradation, and ultimately cell death if not controlled. Blood-sucking arthropods have evolved diverse methods to protect themselves against iron/heme-related damage, as the act of bloodfeeding itself is high risk, high reward process. Pr...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2006
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0602224103